Dermatologist-Recommended Skincare for Anti-Ageing


Written by Dr. Anna H. Chacon, MD FAAD 

What happens to the skin during ageing?

The skin is the largest organ in the body and is constantly exposed to our external environment. During the ageing process, the skin is affected by both intrinsic (internal, natural) and extrinsic (environmental) factors. Ageing in the skin is recognized through the development of wrinkles, increasing laxity, rough-texted appearance, and loss of elasticity. On a molecular level, ageing is accompanied by changes in skin cells as well as functional changes in the essential components of the extracellular matrix such as elastin and collagen. Thus, advances in research of these mechanisms and how they lead to changes within the ageing process have led to investigations in treatment strategies to prevent or reverse the skin’s ageing process.

About Reyou Longevity: Its all about You

Reyou Longevity® is an Australian skincare company geared toward anti-ageing and rejuvenation. All products contain naturally sourced ingredients, and everything is locally made in Australia. Its formulation contains plant stem cells and other actives, as well as Australian native ingredients. Its goals are to maximize skin hydration, stimulate the synthesis of collagen and enhance the metabolism to achieve rejuvenation, improvement in fine lines and wrinkles, texture and tone, to ultimately leave skin with a supple and radiant glow. There is great emphasis on a commitment to the environment while maintaining high-quality standards and transparency regarding how the products are formulated and made. Reyou Longevity® uses premium ingredients that are completely natural, safe, and free from preservatives and artificial toxins.

Plant stem cells and their role in ageing

Since skin ageing is complex and involves the entire epidermis and dermis. To slow or decrease the ageing process, methods are focused on strengthening and protecting stem cells in the skin. Research and investigation have sought to use the right formulation to help stimulate proliferation of stem cells in our epidermis. Plant stem cells have demonstrating properties of anti-ageing, as they are able to stimulate fibroblasts to make collagen, which then stimulates regeneration within the skin. An important agent in plant stem cell extracts that support its anti-ageing process includes kinetin, a compound that is considered to be a strong antioxidant which protects nuclei acids and proteins from an oxidative process. This agent helps to enable cells to remove excess free radicals to protect them from potential oxidative stressors.

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 Products and featured ingredients

Reyou Longevity® products include the Anti-Aging Stem Cell Serum and Moisturizer, which can be used individually or combined together as a starter kit. Their products are naturally sourced, locally made, and free of oils, fragrances, parabens, and cruelty-free.

The Anti-Aging Serum contains a blend of plant stem cells including the Australian Kakadu plum and hyaluronic acid to stimulate rejuvenation, improve wrinkles and fine lines as well as skin texture and tone to promote a more youthful appearance. The main active ingredients include hyaluronic acid, Kakadu plum, and a blend of plant stem cells derived from Agave, Acai, and Eucalyptus plants.

The Australian native Kakadu plum (Terminalia ferdinandiana) fruit has antioxidant and antimicrobial properties and large amounts of vitamin C (also known as ascorbic acid). The Kakadu plum has the highest known concentration of vitamin C compared to other natural food sources and as a unique ingredient, it hydrates, provides antioxidants, vitamins and minerals to help decrease the likelihood of blemishes.

Hyaluronic acid is a key molecule involved in skin moisture and is uniquely capable of retaining water. The complexity of hyaluronic acid metabolism is illustrated by multiple sites for control of its synthesis, position, and cell and protein association and degradation. Understanding and incorporating hyaluronic acid and including it as a main ingredient has helped retain skin moisture within the precuts, while assisting with collagen stimulation, helping the skin appear hydrated, firm, smooth and with a greater sense of elasticity. Hyaluronic acid through its water retention helps to also protect the skin from exposures and stressors in the environment.

The plant stem cell blend which is derived from agave, acai, and eucalyptus includes the moisture-binding properties of agave nectar and the activity of phenolic metabolites produced by açaí palms to stimulate antioxidants to enhance cellular metabolism and optimize anti-ageing benefits. Eucalyptus stem cell technology helps to purify skin through the elimination of cellular wastes and toxins, decreasing oxidized oils and reducing free radicals caused by environmental stressors.

The Anti-Ageing Stem Cell Moisturizer is a hydrating blend of plant stem cells and vegan peptides. Its formula is high in collagen, omega 7, and vitamins A, B1, B2, and C. The main active ingredients in this product include marine-based collagen sourced from seaweed, vegan peptide derived from rice proteins, sea buckthorn berry which is naturally high in omega 7 fatty acids, vitamins A, B1, B2, and C; and plant stem cell blends derived from Agave and Acai plants.

Marine-based collagen derived from seaweed are similar to the collagen in humans in terms of safety, bioavailability and activities. Supplementation improves sebum production, skin elasticity and dermal markers. Marine collagen peptides in addition to antioxidants are safe and effective to improve the skin without risking oxidative damage.

 Vegan peptides from rice proteins also help improve the texture of the skin, promote collagen production and improve the appearance of fine lines.

Sea buckthorn berry contains fatty acids such as omega 7 which provides a unique oil that is beneficial in healthcare, biomedicine and cosmetics. It also is naturally high in vitamins A, C, B1 and B2.

Plant stem cell blends from açaí and agave help build on moisture-binding properties of agave nectar and the activity of phenolic metabolites from the açaí palms to maximize hydration as well as antioxidants to enhance rejuvenation.  

Concluding remarks

Plant stem cells in cosmetics, cosmeceuticals, skincare and dermatology is a growing trend within skincare with meaningful chances in human skin. The regeneration of plants provides a unique process at the cellular and tissue levels. After an injury, plant stem cells have the ability to regenerate and stimulate themselves. These unique properties have sparked an interest and focus in the development of cosmetics, cosmeceuticals and skincare to study how plant stem cell extracts and phytohormones can influence our skin and mitigate the ageing process. 

 

References:

Zhang S, Duan E. Fighting against Skin Aging: The Way from Bench to Bedside. Cell Transplant. 2018;27(5):729-738. doi:10.1177/0963689717725755

Taub AF, Pham K. Stem Cells in Dermatology and Anti-aging Care of the Skin. Facial Plast Surg Clin North Am. 2018;26(4):425-437. doi:10.1016/j.fsc.2018.06.004

Trehan S, Michniak-Kohn B, Beri K. Plant stem cells in cosmetics: current trends and future directions. Future Sci OA. 2017;3(4):FSO226. Published 2017 Jul 12. doi:10.4155/fsoa-2017-0026

Miastkowska M, Sikora E. Anti-aging properties of plant stem cell extracts. Cosmetics 2018; 5(4), 55; https://doi.org/10.3390/cosmetics5040055

Williams DJ, Edwards D, Pun S, et al. Organic acids in Kakadu plum (Terminalia ferdinandiana): The good (ellagic), the bad (oxalic) and the uncertain (ascorbic). Food Res Int. 2016;89(Pt 1):237-244. doi:10.1016/j.foodres.2016.08.004

De Luca C, Mikhal'chik EV, Suprun MV, Papacharalambous M, Truhanov AI, Korkina LG. Skin Antiageing and Systemic Redox Effects of Supplementation with Marine Collagen Peptides and Plant-Derived Antioxidants: A Single-Blind Case-Control Clinical Study. Oxid Med Cell Longev. 2016;2016:4389410. doi:10.1155/2016/4389410

About the author:

Dr. Anna H. Chacon, MD FAAD is a board-certified dermatologist


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